Healthcare demand for hospital beds is a concern in both private and public institutions. Conventional beds are cumbersome and do not consider caregiver’s health, nor patient’s stress and discomfort, which have consequences on the rehabilitation process. For these reasons, a mechatronic SmartBed system is proposed, designed with a user-friendly interface that empowers the patient and caregiver to move the bed into complex positions that improves the person’s quality of life and reduce the risk of death. In this paper, the details of the design and development process of the SmartBed, with special focus on the interactive user interface for controlling the system, along with preliminary results of the interaction between test subjects and the hospital bed is presented.